In ancient time, Anyawadee, the venom queen, fell for Chaiyawongsa, Prince of Indakesa and decided to use black magic to lure him. The prince’s fiancée, Princess Kamyhadfah, together with King and Queen of Indakesa, tried to reveal the venom’s authentic form. The Princess ordered Maneewan, a beautiful dancer, to hold a ritual that will destroy the Venom’s spell. The plan tragically led to the death of many people and Chaiyawongsa fell for Maneewan instead. However, Anyawadee’s soul was finally suppressed within the sacred idol by the Naga Gem for thousand years since then.

At present, Chaiyawongsa reincarnated as Saruch without any love or hate feeling from the past. On the other hand, Anyawadee still could not leave behind the malice and tried to bring back her love. The venom queen started to take revenge on everybody who took part in separating the prince and her, including Princess Khamyhadfah and Maneewan, who also reincarnated as Saricha and Yaimai respectively.

Anyavadee gave a curse that Yaimai would become a snake under her power. Only the Naga gem could help remove the curse. And everything should be done before Yaimai reached 25, which was less than a month.